povidone iodine

? Legal status Routes topical, when formulated

Povidone-iodine (PVPI) is a water-soluble complex of iodine with polyvinylpyrrolidone (PVP), with from 9.0% to 12.0% available iodine, calculated on a dry basis[1].

PVPI can be further formulated into topical antiseptic products as a solution (with surfactants and/or alcohol), aerosol or ointment at concentrations from 7.5% to 10%. These products are sold over-the-counter (OTC) and used in hospitals for cleansing and disinfecting the skin, preparing the skin preoperatively and treating infections susceptible to iodine.

It works through disruption of pathogen cell walls.

Notes and references ^ United States Pharmacopeia

See also Tincture of iodine Lugol's iodine Betadine Iodophor This antimicrobial-related article is a stub. You can help Wikipedia by expanding it. [show] v • d • eAntiseptics and disinfectants (D08) Acridine derivatives Ethacridine lactate · Aminoacridine · Euflavine Biguanides and amidines Dibrompropamidine · Chlorhexidine · Propamidine · Hexamidine · Polihexanide Phenol and derivatives Hexachlorophene · Policresulen · Phenol · Triclosan · Chloroxylenol · Biphenylol Nitrofuran derivatives Nitrofurazone Iodine products Iodine/octylphenoxypolyglycolether · Povidone-iodine · Diiodohydroxypropane Quinoline derivatives Dequalinium · Chlorquinaldol · Oxyquinoline · Clioquinol Quaternary ammonium compounds Benzalkonium · Cetrimonium · Cetylpyridinium · Cetrimide · Benzoxonium chloride · Didecyldimethylammonium chloride Mercurial products Mercuric amidochloride · Phenylmercuric borate · Mercuric chloride · Mercurochrome · Thiomersal · Mercuric iodide Silver compounds Silver nitrate Alcohols Propanol (Propyl Alcohol · Isopropanol (Isopropyl Alcohol) · Ethanol (Ethyl Alcohol) · Other Potassium permanganate · Sodium hypochlorite · Hydrogen peroxide · Eosin · Tosylchloramide sodium · [show] v • d • eMedicated dressings (D09) Ointment dressings

with anti-infectives Framycetin - Fusidic acid - Nitrofural - Phenylmercuric nitrate - Benzododecinium - Triclosan - Cetylpyridinium - Aluminium chlorohydrate - Povidone-iodine - Clioquinol - Benzalkonium - Chlorhexidine - Iodoform Other Zinc bandages - Soft paraffin dressings [show] v • d • eOther dermatological preparations (D11) Medicated shampoos Cetrimide - Cadmium compounds - Selenium compounds - Povidone-iodine - Sulfur compounds - Xenysalate Other dermatologicals seborrhoeic dermatitis/dandruff (Lithium succinate, Pyrithione zinc)

skin whitening/depigmenting (Hydroquinone, Mequinol, Monobenzone)

anti-inflammatory/Immunomodulators (Oxaceprol, Gamolenic acid,